{
  "id": 409772,
  "title": "Beginners understanding of GO graph",
  "url": "/competitions/cafa-5-protein-function-prediction/discussion/409772",
  "author_name": "Simon Veitner",
  "post_date": "2023-05-12T14:11:38.456000",
  "votes": 6,
  "comment_count": 0,
  "views": 0,
  "content": "<p>Hello,<br>\nas I'm a beginner on this field i try to familiarize myself with the concepts needed for this competition.<br>\nMy starting point is the gene ontology (GO).<br>\nIn my understanding it's a way of organizing our knowledge about genes.<br>\nWe have three roots</p>\n<ul>\n<li>Biological Process</li>\n<li>Molecular Function</li>\n<li>Cellular Component</li>\n</ul>\n<p>As we further proceed down in the graph the information get's more and more specialized.<br>\nProteins can get annotated with a bunch of GO-IDs each referring to a different functionality, a \"job\" the protein has to do.<br>\nAlso a similar job (GO annotation) can be done by multiple proteins.<br>\nA little bit different way of displaying the knowledge in our graph than what i've seen in the popular notebooks can be found <a href=\"https://www.kaggle.com/code/simonveitner/eda-of-go-graph\" target=\"_blank\">in my notebook</a>.<br>\nIf I understood something wrong or you can provide additional info that could be helpful, i would be thankful.</p>",
  "messages": [
    {
      "id": 2256479,
      "postDate": "2023-05-12T14:11:38.457Z",
      "content": "<p>Hello,<br>\nas I'm a beginner on this field i try to familiarize myself with the concepts needed for this competition.<br>\nMy starting point is the gene ontology (GO).<br>\nIn my understanding it's a way of organizing our knowledge about genes.<br>\nWe have three roots</p>\n<ul>\n<li>Biological Process</li>\n<li>Molecular Function</li>\n<li>Cellular Component</li>\n</ul>\n<p>As we further proceed down in the graph the information get's more and more specialized.<br>\nProteins can get annotated with a bunch of GO-IDs each referring to a different functionality, a \"job\" the protein has to do.<br>\nAlso a similar job (GO annotation) can be done by multiple proteins.<br>\nA little bit different way of displaying the knowledge in our graph than what i've seen in the popular notebooks can be found <a href=\"https://www.kaggle.com/code/simonveitner/eda-of-go-graph\" target=\"_blank\">in my notebook</a>.<br>\nIf I understood something wrong or you can provide additional info that could be helpful, i would be thankful.</p>",
      "rawMarkdown": "Hello,\nas I'm a beginner on this field i try to familiarize myself with the concepts needed for this competition.\nMy starting point is the gene ontology (GO).\nIn my understanding it's a way of organizing our knowledge about genes.\nWe have three roots\n- Biological Process\n- Molecular Function\n- Cellular Component\n\nAs we further proceed down in the graph the information get's more and more specialized.\nProteins can get annotated with a bunch of GO-IDs each referring to a different functionality, a \"job\" the protein has to do.\nAlso a similar job (GO annotation) can be done by multiple proteins.\nA little bit different way of displaying the knowledge in our graph than what i've seen in the popular notebooks can be found [in my notebook](https://www.kaggle.com/code/simonveitner/eda-of-go-graph).\nIf I understood something wrong or you can provide additional info that could be helpful, i would be thankful.\n",
      "votes": 6
    }
  ],
  "comments": [],
  "raw_markdown_by_id": {
    "2256479": "Hello,\nas I'm a beginner on this field i try to familiarize myself with the concepts needed for this competition.\nMy starting point is the gene ontology (GO).\nIn my understanding it's a way of organizing our knowledge about genes.\nWe have three roots\n- Biological Process\n- Molecular Function\n- Cellular Component\n\nAs we further proceed down in the graph the information get's more and more specialized.\nProteins can get annotated with a bunch of GO-IDs each referring to a different functionality, a \"job\" the protein has to do.\nAlso a similar job (GO annotation) can be done by multiple proteins.\nA little bit different way of displaying the knowledge in our graph than what i've seen in the popular notebooks can be found [in my notebook](https://www.kaggle.com/code/simonveitner/eda-of-go-graph).\nIf I understood something wrong or you can provide additional info that could be helpful, i would be thankful.\n"
  }
}