{
  "id": 432272,
  "title": "Similar competitions ",
  "url": "/competitions/cafa-5-protein-function-prediction/discussion/432272",
  "author_name": "Gyula Maloveczky4",
  "post_date": "2023-08-16T17:54:54.092000",
  "votes": 2,
  "comment_count": 5,
  "views": 0,
  "content": "<p>Are there any other protein function prediction competitions?</p>",
  "messages": [
    {
      "id": 2394106,
      "postDate": "2023-08-16T17:54:54.093Z",
      "content": "<p>Are there any other protein function prediction competitions?</p>",
      "rawMarkdown": "Are there any other protein function prediction competitions?",
      "votes": 2
    },
    {
      "id": 2394576,
      "postDate": "2023-08-17T03:09:51.667Z",
      "rawMarkdown": "",
      "votes": 1,
      "isDeleted": true,
      "replies": [
        {
          "id": 2395335,
          "postDate": "2023-08-17T13:11:28.907Z",
          "content": "<p>Thank you very much!<br>\nSo basically this was THE protein function prediction competition, right?</p>",
          "rawMarkdown": "Thank you very much!\nSo basically this was THE protein function prediction competition, right?",
          "replies": [
            {
              "id": 2395746,
              "postDate": "2023-08-17T19:23:40.670Z",
              "rawMarkdown": "",
              "votes": 1,
              "isDeleted": true
            },
            {
              "id": 2395753,
              "postDate": "2023-08-17T19:34:59.107Z",
              "content": "<p>CAFA is generally recognized as the \"main event\" of computational protein function prediction. This is the first time it was held on Kaggle, but it was held 4 times before (hence \"CAFA 5\"). The paper <a href=\"https://www.kaggle.com/nihilisticneuralnet\" target=\"_blank\">@nihilisticneuralnet</a> referenced reports on the CAFA3 results. You can find publications from other CAFA rounds here: <a href=\"https://biofunctionprediction.org/publications/\" target=\"_blank\">https://biofunctionprediction.org/publications/</a></p>\n<p>While thermostability of enzyme variants is an important problem, but it is a highly specific aspect of function. In the novozymes challenge, the question is: \"given an enzyme, at what temperature does it stop working?\"  Whereas in CAFA it is: \"Given a protein sequence, what does it do? (which GO terms are associated with it?)\"</p>\n<p>Other biomedical competitions were held under the framework of the DREAM challenges. <a href=\"https://dreamchallenges.org/\" target=\"_blank\">https://dreamchallenges.org/</a></p>\n<p>One ongoing challenge that is interesting is associating genes and mutations with phenotypes, typically diseases, that is the CAGI challenge: <a href=\"https://genomeinterpretation.org/\" target=\"_blank\">https://genomeinterpretation.org/</a></p>",
              "rawMarkdown": "CAFA is generally recognized as the \"main event\" of computational protein function prediction. This is the first time it was held on Kaggle, but it was held 4 times before (hence \"CAFA 5\"). The paper @nihilisticneuralnet referenced reports on the CAFA3 results. You can find publications from other CAFA rounds here: https://biofunctionprediction.org/publications/\n\nWhile thermostability of enzyme variants is an important problem, but it is a highly specific aspect of function. In the novozymes challenge, the question is: \"given an enzyme, at what temperature does it stop working?\"  Whereas in CAFA it is: \"Given a protein sequence, what does it do? (which GO terms are associated with it?)\"\n\nOther biomedical competitions were held under the framework of the DREAM challenges. https://dreamchallenges.org/\n\nOne ongoing challenge that is interesting is associating genes and mutations with phenotypes, typically diseases, that is the CAGI challenge: https://genomeinterpretation.org/\n",
              "votes": 4
            },
            {
              "id": 2396212,
              "postDate": "2023-08-18T06:09:03.550Z",
              "content": "<p>Thank you!</p>",
              "rawMarkdown": "Thank you!"
            }
          ]
        }
      ]
    }
  ],
  "comments": [
    {
      "id": 2394576,
      "author_name": "",
      "author_url": "",
      "post_date": "2023-08-17T03:09:51.667000",
      "content": "",
      "votes": 1,
      "replies": [
        {
          "id": 2395335,
          "author_name": "Gyula Maloveczky4",
          "author_url": "",
          "post_date": "2023-08-17T13:11:28.907000",
          "content": "<p>Thank you very much!<br>\nSo basically this was THE protein function prediction competition, right?</p>",
          "votes": 0,
          "replies": [
            {
              "id": 2395746,
              "author_name": "",
              "author_url": "",
              "post_date": "2023-08-17T19:23:40.670000",
              "content": "",
              "votes": 1,
              "replies": []
            },
            {
              "id": 2395753,
              "author_name": "Iddo Friedberg",
              "author_url": "",
              "post_date": "2023-08-17T19:34:59.107000",
              "content": "<p>CAFA is generally recognized as the \"main event\" of computational protein function prediction. This is the first time it was held on Kaggle, but it was held 4 times before (hence \"CAFA 5\"). The paper <a href=\"https://www.kaggle.com/nihilisticneuralnet\" target=\"_blank\">@nihilisticneuralnet</a> referenced reports on the CAFA3 results. You can find publications from other CAFA rounds here: <a href=\"https://biofunctionprediction.org/publications/\" target=\"_blank\">https://biofunctionprediction.org/publications/</a></p>\n<p>While thermostability of enzyme variants is an important problem, but it is a highly specific aspect of function. In the novozymes challenge, the question is: \"given an enzyme, at what temperature does it stop working?\"  Whereas in CAFA it is: \"Given a protein sequence, what does it do? (which GO terms are associated with it?)\"</p>\n<p>Other biomedical competitions were held under the framework of the DREAM challenges. <a href=\"https://dreamchallenges.org/\" target=\"_blank\">https://dreamchallenges.org/</a></p>\n<p>One ongoing challenge that is interesting is associating genes and mutations with phenotypes, typically diseases, that is the CAGI challenge: <a href=\"https://genomeinterpretation.org/\" target=\"_blank\">https://genomeinterpretation.org/</a></p>",
              "votes": 4,
              "replies": []
            },
            {
              "id": 2396212,
              "author_name": "Gyula Maloveczky4",
              "author_url": "",
              "post_date": "2023-08-18T06:09:03.550000",
              "content": "<p>Thank you!</p>",
              "votes": 0,
              "replies": []
            }
          ]
        }
      ]
    }
  ],
  "raw_markdown_by_id": {
    "2394106": "Are there any other protein function prediction competitions?",
    "2394576": ""
  }
}