{
  "id": 432421,
  "title": "duplicate sequences in fasta",
  "url": "/competitions/cafa-5-protein-function-prediction/discussion/432421",
  "author_name": "",
  "post_date": "2023-08-17T09:50:15.399948300Z",
  "votes": 1,
  "comment_count": 2,
  "views": 0,
  "content": "<p>I arrived very late in this competition but I'm running to send something. I started to do little data analysis but I found an issues that I need to understand. In fasta file, there are 2731 duplicate sequences. For instance, the protein with id P86567, P86579, P86591, P86573, P86561 have the same sequence: APLMGFQGVR. Obviously they have the same annotations: GO:0110165, GO:0005575, GO:0005576. <br>\nIs it an error or there is a reason because this happens? </p>",
  "messages": [
    {
      "id": "2395118",
      "postDate": "08/17/2023 09:50:15",
      "content": "<p>I arrived very late in this competition but I'm running to send something. I started to do little data analysis but I found an issues that I need to understand. In fasta file, there are 2731 duplicate sequences. For instance, the protein with id P86567, P86579, P86591, P86573, P86561 have the same sequence: APLMGFQGVR. Obviously they have the same annotations: GO:0110165, GO:0005575, GO:0005576. <br>\nIs it an error or there is a reason because this happens? </p>",
      "rawMarkdown": "I arrived very late in this competition but I'm running to send something. I started to do little data analysis but I found an issues that I need to understand. In fasta file, there are 2731 duplicate sequences. For instance, the protein with id P86567, P86579, P86591, P86573, P86561 have the same sequence: APLMGFQGVR. Obviously they have the same annotations: GO:0110165, GO:0005575, GO:0005576. \nIs it an error or there is a reason because this happens?",
      "votes": null
    },
    {
      "id": "2395165",
      "postDate": "08/17/2023 10:31:46",
      "content": "<p>Short answer, given the time. Yes it happens. The sequences you have highlighted are all neuropeptides in different insect species. It just so happens that no changes have occurred to those sequences in the time taken for those species to appear in evolution. Very likely they all have the exact same function, but very rarely two identical sequences in different species can have different functions. Usually those differences are minor though. There are even cases where identical sequences in the same species have slightly different functions (genes expressed in different tissues for example), but again this is relatively uncommon.</p>",
      "rawMarkdown": "Short answer, given the time. Yes it happens. The sequences you have highlighted are all neuropeptides in different insect species. It just so happens that no changes have occurred to those sequences in the time taken for those species to appear in evolution. Very likely they all have the exact same function, but very rarely two identical sequences in different species can have different functions. Usually those differences are minor though. There are even cases where identical sequences in the same species have slightly different functions (genes expressed in different tissues for example), but again this is relatively uncommon.",
      "votes": null
    },
    {
      "id": "2395174",
      "postDate": "08/17/2023 10:39:53",
      "content": "<p>Thank you, I can continue to develop</p>",
      "rawMarkdown": "Thank you, I can continue to develop",
      "votes": null
    }
  ],
  "comments": [
    {
      "id": 2395165,
      "author_name": "biodav",
      "author_url": "",
      "post_date": "08/17/2023 10:31:46",
      "content": "<p>Short answer, given the time. Yes it happens. The sequences you have highlighted are all neuropeptides in different insect species. It just so happens that no changes have occurred to those sequences in the time taken for those species to appear in evolution. Very likely they all have the exact same function, but very rarely two identical sequences in different species can have different functions. Usually those differences are minor though. There are even cases where identical sequences in the same species have slightly different functions (genes expressed in different tissues for example), but again this is relatively uncommon.</p>",
      "votes": null,
      "replies": [
        {
          "id": 2395174,
          "author_name": "marcosarti",
          "author_url": "",
          "post_date": "08/17/2023 10:39:53",
          "content": "<p>Thank you, I can continue to develop</p>",
          "votes": null,
          "replies": []
        }
      ]
    }
  ],
  "raw_markdown_by_id": {
    "2395118": "I arrived very late in this competition but I'm running to send something. I started to do little data analysis but I found an issues that I need to understand. In fasta file, there are 2731 duplicate sequences. For instance, the protein with id P86567, P86579, P86591, P86573, P86561 have the same sequence: APLMGFQGVR. Obviously they have the same annotations: GO:0110165, GO:0005575, GO:0005576. \nIs it an error or there is a reason because this happens?",
    "2395165": "Short answer, given the time. Yes it happens. The sequences you have highlighted are all neuropeptides in different insect species. It just so happens that no changes have occurred to those sequences in the time taken for those species to appear in evolution. Very likely they all have the exact same function, but very rarely two identical sequences in different species can have different functions. Usually those differences are minor though. There are even cases where identical sequences in the same species have slightly different functions (genes expressed in different tissues for example), but again this is relatively uncommon.",
    "2395174": "Thank you, I can continue to develop"
  },
  "source": "meta"
}